仅用于工业应用或科学研究,不可用于人类或动物的临床诊断或治疗,非药用.Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus.Brefeldin A is also an autophagy and mitophagy inhibitor.Brefeldin A is a CRISPR/Cas9 activator.Brefeldin A inhibits HSV-1 and has anti-cancer activity.Brefeldin A (BFA) 是一种内酯抗生素,是蛋白质运输的特定抑制剂。Brefeldin A 阻断分泌蛋白和膜蛋白从内质网向高尔基体的转运。Brefeldin A 也是一种自噬 (autophagy) 和 mitophagy 抑制剂