Panobinostat (LBH589; NVP-LBH589)

仅用于工业应用或科学研究，不可用于人类或动物的临床诊断或治疗，非药用.Panobinostat （LBH589; NVP-LBH589） is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities.Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells.Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma.Panobinostat 诱导细胞凋亡 （apoptosis） 和自噬 （autophagy）。Panobinostat 可用于难治性或复发性多发性骨髓瘤的研究